Professor Anne Chang AM

Senior Principal Research Fellow, Head of the Child Health Respiratory Program, Head of the Child and Maternal Health Division

Qualifications:

Bachelor of Medicine and Bachelor of Surgery, University of Melbourne, 1988 (MBBS); Master of Public Health and Tropical Medicine, James Cook University, 2000 (MPHTM); PhD, University of Melbourne, 1998 (PhD); Fellow, Royal Australasian College of Physicians, 1995 (FRACP); Fellow, Thoracic Society of Australia and New Zealand (FThorSoc); Fellow, Asian Pacific Society of Respirology, 2013; Fellow, Australian Academy of Health and Medical Science (FAHMS)

Approved level of HDR supervision at Charles Darwin University:

Principal Supervisor for PhD

Location:

Brisbane, Darwin - Royal Darwin Hospital campus

Biography:

Professor Anne Chang AM is an established leading researcher with international recognition in cough, bronchiectasis and evidence-based medicine (EBM) related to paediatric respiratory medicine. She has helped develop and apply EBM for respiratory illnesses nationally and internationally. She is the editor of two EBM series, one on respiratory medicine and the other on Indigenous health.

Professor Chang is also responsible for changing paradigms in the investigation and management of paediatric cough leading to earlier diagnosis of bronchiectasis, describing a pre-bronchiectasis condition (PBB), the inclusion of respiratory symptoms in primary care child assessments (Northern Territory and Queensland) and the establishment of the first international Indigenous collaborative respiratory study.

Professor Anne Chang AM
Email
Research Themes
  • Child and Maternal Health
  • Respiratory Health

 

  1. Ruffles TJC, Goyal V, Marchant JM, Masters IB, Yerkovich ST, Buntain HM, Cook A, Schultz A, Upham JW, Champion A, Versteegh L, Chang AB. Duration of amoxicillin-clavulanate for protracted bacterial bronchitis in children (DACS): a multi-centre, double blind, randomised controlled trial. Lancet Respir Med. 2021; 9(10):1121-1129. doi: 10.1016/S2213-2600(21)00104-1.
  2. O'Grady KF, Grimwood K, Torzillo PJ, Rablin S, Lovie-Toon Y, Kaus M, Arnold D, Roberts J, Buntain H, Adsett D, King A, Scott M, Anderson J, Toombs M, Chang AB. Effectiveness of a chronic cough management algorithm at the transitional stage from acute to chronic cough in children: a multi-centre randomised controlled trial. Lancet Child & Adolescent Health 2019;3:889-98
  3. Goyal V, Grimwood K, Ware RS, Byrnes CA, Morris PS, Masters IB, McCallum GB, Binks MJ, Marchant JM, Smith-Vaughan HS, O'Grady KF, Champion A, Buntain H, Schultz A, Chatfield M, Torzillo PJ, Chang AB. Efficacy of oral antibiotics for non-severe exacerbations of bronchiectasis in children (BEST 1): A multi-centre, double-blind, double-dummy, randomised placebo-controlled trial. Lancet Respir Med. 2019; 7(9):791-801. doi: 10.1016/S2213-2600(19)30254-1.
  4. Goyal V, Grimwood K, Byrnes CA, Morris PS, Masters IB, Ware RS, McCallum GB, Binks MJ, Marchant JM, Van Asperen PP, O'Grady KF, Champion A, Buntain H, Petsky H, Torzillo PJ, Chang AB. Amoxicillin-clavulanate versus azithromycin for respiratory exacerbations in children with bronchiectasis (BEST-2): A multi-centre, double-blind, non-inferiority randomised controlled trial. Lancet 2018;392(10154):1197-1206. doi: 10.1016/S0140-6736(18)31723-9. 
  5. Chang AB, Bush A, Grimwood K. Diagnosis and management of children with bronchiectasis. Lancet 2018 Sep 8;392(10150):866-879. doi: 10.1016/S0140-6736(18)31554-X
  6. Chalmers JD, Chang AB, Chotirmall SJ, Dhar R, McShane PJ. Bronchiectasis. Nature Rev Disease Primers 2018;4(1):45. doi: 10.1038/s41572-018-0042-3
  7. Chang AB, Grimwood K. Antibiotics for childhood pneumonia: do we really know how long to treat? N Engl J Med 2020; 383(1):77-79. doi: 10.1056/NEJMe2016328
  8. Chang AB, Zacharasiewicz A, Goyal V, Boyd J, Alexopoulou E, Aliberti S, Bell L, Bush A, Claydon A, Constant C, Fortescue R, Hill AT, Karadag B, Powell Z, Wilson C, Grimwood K, Kantar A; other members of Child-BEAR-Net. Task Force report: European Respiratory Society statement for defining respiratory exacerbations in children and adolescents with bronchiectasis for clinical trials. Eur Respir J. 2022 Nov 3;60(5):2200300 doi: 10.1183/13993003.00300-2022. 
  9. Chang AB, Fortescue R, Grimwood K, Alexopoulou E, Bell L, Boyd J, Bush A, Chalmers JD, Hill AT, Karadag B, Midulla F, McCallum GB, Powell Z, Snijders D, Song WJ, Tonia T, Wilson C, Zacharasiewicz A, Kantar A. European Respiratory Society guidelines for the management of children and adolescents with bronchiectasis. Eur Respir J 2021: 58(2):2002990. doi: 10.1183/13993003.02990-2020 
  10. de Benedictis FM, Kerem E, Chang AB, Colin AA, Zar HJ, Bush A. Complicated pneumonia in children. Lancet. 2020; 396(10253):786-798.
     

For more publications by Prof. Anne Chang visit: https://researchers.cdu.edu.au/en/persons/anne-chang/publications/

  1. MEDIA RELEASE | Five Menzies researchers awarded NHMRC Investigator Grants
  2. Researchers at CDU some of the most influential in their fields
  3. Preventing infant wheeze and childhood asthma
  4. 2021 Howard Williams Medal winner announced
  5. CDU academics named among world’s most influential
  6. Media alert | Outcomes of protracted bacterial bronchitis in children: A 5‐year prospective cohort study
  7. Acute lower respiratory infections in Indigenous infants in the NT
  8. $440 million funding boost for vital health and medical research for all stages of life
  9. The Lancet | Anne Chang: a champion of childhood lung health
  10. Menzies clinician-researchers receive NHMRC funding
  11. $12 Million NT Investment aims to save lives
  12. Evidence informs chronic cough guidelines
  13. Red hot Alice puts mums and bubs at risk
  14. Menzies leaders inducted into important new health and medical academy
  15. NHMRC fellowship snapshot: Professor Anne Chang
  16. Cough, step and jump: a profile of Professor Anne Chang
  17. Menzies' lung and cancer programs win $5 million in 'research excellence' funding